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Over the year, there has been a steady increase of microbes resistance to antimicrobial treatments, leading to a growing global public health concern. This resistance is threatening the effective treatment of infectious diseases and combating this threat is a major concern for the EMA and the European Medicines Regulatory Network.

Infections by multidrug-resistant bacteria are estimated to cause 25,000 deaths in the EU every year. This places a huge burden on healthcare systems and society. Development of resistance is a natural phenomenon and occurs when microorganisms replicate themselves incorrectly or when resistant traits are exchanged between them. However, the over use and misuse of antimicrobials can and does accelerate resistance. The lack of new types of antibiotics exacerbates this problem.

 

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